When someone lacks self-respect, they live their life miserably. They shoulder the burdens of regret, shame, loathing and blame. They are prone to engaging themselves to self-destructive behavior because they have little value for themselves.
The guide is not outside, the guide is within you. One has to go deeper into one's own being to find God and the guide. Once the inner guide is found there are no more mistakes, no repentance, no guilt.