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What is Pineocytoma of pineal gland?

size of pineal gland, 5x6x7mm. What symptom is expected if it become bigger?


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  1. Pineal tumors may cause headache, vomiting, and seizures due to the increase in pressure within the head that results from the enlarging tumor mass. Endocrinologic effects may also be observed. Some patients may become hypogonadal with regression of secondary sex characteristics, while others may undergo precocious puberty because of secretion of chorionic gonadotropin. Diabetes insipidus is frequently associated and is usually due to tumor invasion of the hypothalamus and posterior pituitary. Invasion of the pituitary stalk may interfere with the ongoing inhibition of prolactin secretion by dopamine from the hypothalamus, resulting in elevated serum prolactin levels, a finding that may lead to a mistaken diagnosis of prolactinoma. Treatment consists of surgical relief of the increased intracranial pressure and X-ray therapy.

  2. Pineal region tumors are usually germ cell tumors (eg, germinoma, choriocarcinoma, yolk-sac tumor, teratoma). Other primary pineal tumors include pineocytoma and the rare malignant pineoblastoma.
    Pineocytoma-A slow growing type of brain tumor that occurs in or around the pineal gland, a tiny organ near the center of the brain.
    Pineal tumors occur about four times more frequently than in girls.
    The essential symptoms are those of increased intracranial pressure (headache, vomiting), together with an inability to look upward. Precocious sexual deveopment may occur in boys.
    Pineal tumors frequently interfere with the flow of cerebrospinal fluid and cause obstructive hydrocephalus.
    The presence of a pineal tumor may be suspected on the basis of the symptoms and signs, especially when there is evidence of increased intracranial pressure and the child cannot look upward. A confirmation of the diagnosis is achieved through pneumoencelography (injection of air into the fluid containing spaces of the brain, followed by x-ray examination.)
    Because of its location deep in the brain, it is extremely hazardous to attempt to remove a pineal tumor. Treatment usually consists of a shunting operation to relieve the increased intracranial pressure, followed by x-ray therapy. Patients treated in this manner often do well for many years.
    When less radical measures, such as an operative procedure to shunt the flow of cerebrospinal fluid, have failed, and when tumor continues to grow despite x-ray treatment. Such operations are extremely hazardous and the mortality rate is high.
    Please nte that I am not a medical professional.

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