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What chemical could you put on a rag and hold to someone's face to make them lose consciousness?

This is for a work of fiction. I’ve heard that ether or cholorform could be used. Anything else?


  1. I’m not sure that we should answer that because you might be using it for some other purpose. and Josh ether used to be used in surgery to put people to sleep I know because it was used on my in the 50’s and 60’s.

  2. I don’t think this question is appropriate for this forum – you don’t want the wrong person to get this information.

  3. It is a work of fiction. Make something up. Make up some entirely new chemical sounding name. Maybe you will become famous for it.

  4. Lol hasn’t anyone read/seen “Fight Club”? It gives you instruction on how to make bombs. I’m sure this doesn’t really matter compared to that.

  5. Toad,
    When we see movies when a perp kidnaps someone by placing a moist rag over their mouths it’s assumed by the average person to be chloroform, although this is not necessarily the case, especially if the intent was to keep the target alive. This is why chloroform hasn’t been used as an anesthetic by the medical community for decades, since even a tad too much could prove fatal or even if the patient were to survive could easily result in long term internal organ damage.
    This is why ether began to be used as a preferred anesthetic to chloroform. (BTW, ignore that ignoramus that claims that ether will only get you high as he obviously has no understanding of the drugs he’s taking or in this case, inhaling) Ether used as an anesthetic inhalant, however, had problems of its own such as being highly flammable and producing very undesirable post-anesthetic side effects like nausea and vomiting such that Ether is no longer used in the medical community for this purpose. The flammability of ether gave way to use of non-flammable anesthetics such as Halothane, yet even this drug has also produced its share of unwanted side effects such as severe liver injury in some patients that led to halothane hepatitis, and malignant hypothermia in susceptible patients that would occur from repeated exposures. This led to the demise of Halothane as an acceptable inhaled anesthetic except by vets or some 3rd world countries as I explain below.
    The following are the five most commonly used inhalant anesthetics that can answer your question of inducing unconsciousness when a rag is drenched in the chemical and placed over the subject’s face:
    Halothane *
    And of these, the most commonly used are isoflurane, sevoflurane, and desflurane. Their use began in the 1980’s after it was discovered that Halothane Hepatitis had a 30-70% mortality rate.
    * Since Halothane requires repeated exposures to induce its undesirable effects, it is still a common method of inducing coma in the medical communities of third world countries and by Veterinarians.

  6. So, chloroform actually takes about five minutes of constants inhalation before the person is rendered unconsious. It would probably be better to use some form of injection or something.

  7. I’ve recently written a book ( 13 Angels) in which a serial abductor uses isoflurane to render victims unconscious. I also realized that thus information was not nessessary for the plot to work, and have since changed the story.


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