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Marijuana, melatonin, and the pineal gland?

I have a few questions about how the three are related:

1) Is melatonin produced by the pineal gland? Also, is DMT (Dimethyltryptamine) produced by the pineal gland?

2) Does Marijuana increase, decrease, or have any effect on melatonin production in the short-term and long-term? Does Marijuana affect the pineal gland in any way?

3) I have also heard a conspiracy theory that certain government put fluoride in water supplies because fluoride supposedly affects the pineal gland in some way as to make it less sensitive to DMT. HYPOTHETICALLY SPEAKING, if there were fluoride in our water supply or our pineal gland was affected in some way by this, would it also change melatonin production and possibly interfere with sleep patterns?

This is not for school, just curiousity. I apologize for all the questions and 10 pts to the best answer.

Thanks

3 Comments

  • But the theory strikes me as hopelessly implausible, and I cannot imagine the motivation behind destroying the pineal glands of the population. Why? Why not just take their tax money and start wars with it? The people let the government get away with that, and they are not even sleeping.

    I would have to say CONTROL to the above post by Micheal

  • 1) Yes and yes.

    2) Yes, it would decrease melatonin. THC mimics endocannabinoid action; endocannabinoids block presynaptic glutamate release. Glutamate acts upon the pineal gland.

    3) That’s a pretty crazy conspiracy theory. Why would “the government” care about sensitivity of the pineal gland to DMT? The pineal *PRODUCES* DMT. As far as I know, DMT does not have an autocrine effect upon the pineal gland (autocrine = when a hormone acts upon the gland that produces it). But to directly answer your actual question, fluoride does accumulate in the pineal gland. And if that affected pineal function then yes, it would affect melatonin. And yes, messing with melatonin can affect sleep patterns.

    But the theory strikes me as hopelessly implausible, and I cannot imagine the motivation behind destroying the pineal glands of the population. Why? Why not just take their tax money and start wars with it? The people let the government get away with that, and they are not even sleeping.

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