If you take a heart out of the body, what homeostatic changes will occur that can lead to tissue damage?

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If you take a heart out of the body, it will keep beating. What homeostatic changes however, will occur that can lead to tissue damage? What could you do to prevent this damage? (A clue here is to think what happens to exposed moist tissue in air?)

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Huge

Infection from air borne bacteria, drying out of the tissue and tissue change due to temperature would be my guess. To prevent damage submerge in saline solution.

saz17

It wont keep beating forever – cardiac cells need a supply of oxygen just like other cells. You can fling it in ice, but ishaemic damage still occurs which causes the inflammation that leads to acute rejection in transplantation. No blood flow isnt a good thing either, osmotic pressure and all that jazz. Of course the bloody thing will dry out.

Ketan P

The blood it pumps won’t reach other tissues. There’ll be necrosis all over. Moreover, I didn’t get the context of your question. Bye. TC.

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